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Comparison of In Vivo and In Vitro Pharmacodynamics of a Humanized Regimen of 600 Milligrams of Ceftaroline Fosamil Every 12 Hours against Staphylococcus aureus at Initial Inocula of 10(6) and 10(8) CFU per Milliliter

In light of the in vivo/in vitro discordance among beta-lactams against Gram-negative pathogens, we compared the in vivo pharmacodynamics of humanized ceftaroline against 9 Staphylococcus aureus strains (MICs of 0.13 to 1 mg/liter) from published in vitro studies using standard and high inocula in t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: So, Wonhee, Crandon, Jared L., Zhanel, George G., Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249378/
https://ncbi.nlm.nih.gov/pubmed/25136006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03652-14
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