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Characterization of a Lipopolysaccharide-Targeted Monoclonal Antibody and Its Variable Fragments as Candidates for Prophylaxis against the Obligate Intracellular Bacterial Pathogen Coxiella burnetii

Our previous study demonstrated that treatment of Coxiella burnetii with the phase I lipopolysaccharide (PI-LPS)-targeted monoclonal antibody (MAb) 1E4 significantly inhibited C. burnetii infection in mice, suggesting that 1E4 is a protective MAb. To determine whether passive transfer of antibodies...

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Bibliografski detalji
Izdano u:Infect Immun
Glavni autori: Peng, Ying, Schoenlaub, Laura, Elliott, Alexandra, Mitchell, William J., Zhang, Guoquan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249325/
https://ncbi.nlm.nih.gov/pubmed/25114119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01695-14
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