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Damage to the Blood-Brain Barrier during Experimental Cerebral Malaria Results from Synergistic Effects of CD8(+) T Cells with Different Specificities

CD8(+) T cells play a pathogenic role in the development of murine experimental cerebral malaria (ECM) induced by Plasmodium berghei ANKA (PbA) infection in C57BL/6 mice. Only a limited number of CD8(+) epitopes have been described. Here, we report the identification of a new epitope from the berghe...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Poh, Chek Meng, Howland, Shanshan W., Grotenbreg, Gijsbert M., Rénia, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249313/
https://ncbi.nlm.nih.gov/pubmed/25156726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02180-14
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