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Immunogenicity and In Vitro and In Vivo Protective Effects of Antibodies Targeting a Recombinant Form of the Streptococcus mutans P1 Surface Protein

Streptococcus mutans is a major etiologic agent of dental caries, a prevalent worldwide infectious disease and a serious public health concern. The surface-localized S. mutans P1 adhesin contributes to tooth colonization and caries formation. P1 is a large (185-kDa) and complex multidomain protein c...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Batista, Milene Tavares, Souza, Renata D., Ferreira, Ewerton L., Robinette, Rebekah, Crowley, Paula J., Rodrigues, Juliana F., Brady, L. Jeannine, Ferreira, Luís C. S., Ferreira, Rita C. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249279/
https://ncbi.nlm.nih.gov/pubmed/25225243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02074-14
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