Gene Deletions in Mycobacterium bovis BCG Stimulate Increased CD8(+) T Cell Responses

Mycobacteria, the etiological agents of tuberculosis and leprosy, have coevolved with mammals for millions of years and have numerous ways of suppressing their host's immune response. It has been suggested that mycobacteria may contain genes that reduce the host's ability to elicit CD8(+)...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Panas, Michael W., Sixsmith, Jaimie D., White, KeriAnn, Korioth-Schmitz, Birgit, Shields, Shana T., Moy, Brian T., Lee, Sunhee, Schmitz, Joern E., Jacobs, William R., Porcelli, Steven A., Haynes, Barton F., Letvin, Norman L., Gillard, Geoffrey O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249275/
https://ncbi.nlm.nih.gov/pubmed/25287928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02100-14
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