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Fine-Tuning of the Fatty Acid Pathway by Synthetic Antisense RNA for Enhanced (2S)-Naringenin Production from l-Tyrosine in Escherichia coli

Malonyl coenzyme A (malonyl-CoA) is an important precursor for the synthesis of natural products, such as polyketides and flavonoids. The majority of this cofactor often is consumed for producing fatty acids and phospholipids, leaving only a small amount of cellular malonyl-CoA available for produci...

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Veröffentlicht in:Appl Environ Microbiol
Hauptverfasser: Wu, Junjun, Yu, Oliver, Du, Guocheng, Zhou, Jingwen, Chen, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249181/
https://ncbi.nlm.nih.gov/pubmed/25239896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.02411-14
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