HIV-1 Entry in SupT1-R5, CEM-ss, and Primary CD4(+) T Cells Occurs at the Plasma Membrane and Does Not Require Endocytosis

Cytoplasmic entry of HIV-1 requires binding of the viral glycoproteins to the cellular receptor and coreceptor, leading to fusion of viral and cellular membranes. Early studies suggested that productive HIV-1 infection occurs by direct fusion at the plasma membrane. Endocytotic uptake of HIV-1 was f...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Herold, Nikolas, Anders-Ößwein, Maria, Glass, Bärbel, Eckhardt, Manon, Müller, Barbara, Kräusslich, Hans-Georg
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249123/
https://ncbi.nlm.nih.gov/pubmed/25253335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01543-14
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