Mutations to PB2 and NP Proteins of an Avian Influenza Virus Combine To Confer Efficient Growth in Primary Human Respiratory Cells

Influenza pandemics occur when influenza A viruses (IAV) adapted to other host species enter humans and spread through the population. Pandemics are relatively rare due to host restriction of IAV: strains adapted to nonhuman species do not readily infect, replicate in, or transmit among humans. IAV...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Danzy, Shamika, Studdard, Lydia R., Manicassamy, Balaji, Solorzano, Alicia, Marshall, Nicolle, García-Sastre, Adolfo, Steel, John, Lowen, Anice C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249088/
https://ncbi.nlm.nih.gov/pubmed/25210184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01093-14
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