Identification of Molecular Markers Associated with Alteration of Receptor-Binding Specificity in a Novel Genotype of Highly Pathogenic Avian Influenza A(H5N1) Viruses Detected in Cambodia in 2013

Human infections with influenza A(H5N1) virus in Cambodia increased sharply during 2013. Molecular characterization of viruses detected in clinical specimens from human cases revealed the presence of mutations associated with the alteration of receptor-binding specificity (K189R, Q222L) and respirat...

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Udgivet i:J Virol
Main Authors: Rith, Sareth, Davis, C. Todd, Duong, Veasna, Sar, Borann, Horm, Srey Viseth, Chin, Savuth, Ly, Sovann, Laurent, Denis, Richner, Beat, Oboho, Ikwo, Jang, Yunho, Davis, William, Thor, Sharmi, Balish, Amanda, Iuliano, A. Danielle, Sorn, San, Holl, Davun, Sok, Touch, Seng, Heng, Tarantola, Arnaud, Tsuyuoka, Reiko, Parry, Amy, Chea, Nora, Allal, Lotfi, Kitsutani, Paul, Warren, Dora, Prouty, Michael, Horwood, Paul, Widdowson, Marc-Alain, Lindstrom, Stephen, Villanueva, Julie, Donis, Ruben, Cox, Nancy, Buchy, Philippe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Genetic Diversity and Evolution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248976/
https://ncbi.nlm.nih.gov/pubmed/25210193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01887-14
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