Induced Maturation of Human Immunodeficiency Virus

HIV-1 assembles at the plasma membrane of virus-producing cells as an immature, noninfectious particle. Processing of the Gag and Gag-Pol polyproteins by the viral protease (PR) activates the viral enzymes and results in dramatic structural rearrangements within the virion—termed maturation—that are...

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Bibliographic Details
Published in:J Virol
Main Authors: Mattei, Simone, Anders, Maria, Konvalinka, Jan, Kräusslich, Hans-Georg, Briggs, John A. G., Müller, Barbara
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248963/
https://ncbi.nlm.nih.gov/pubmed/25231305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02271-14
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