Development of Dose-Response Models of Creutzfeldt-Jakob Disease Infection in Nonhuman Primates for Assessing the Risk of Transfusion-Transmitted Variant Creutzfeldt-Jakob Disease

Estimates for the risk of transmitting variant Creutzfeldt-Jakob disease (vCJD) via blood transfusion have relied largely on data from rodent experiments, but the relationship between dose (amount of infected blood) and response (vCJD infection) has never been well quantified. The goal of this study...

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Bibliographic Details
Published in:J Virol
Main Authors: Huang, Yin, Gregori, Luisa, Anderson, Steven A., Asher, David M., Yang, Hong
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Prions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248962/
https://ncbi.nlm.nih.gov/pubmed/25231313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01805-14
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