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A Cell-Autonomous Molecular Cascade Initiated by AMP-Activated Protein Kinase Represses Steroidogenesis

Steroid hormones regulate essential physiological processes, and inadequate levels are associated with various pathological conditions. In testosterone-producing Leydig cells, steroidogenesis is strongly stimulated by luteinizing hormone (LH) via its receptor leading to increased cyclic AMP (cAMP) p...

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Bibliographic Details
Published in:Mol Cell Biol
Main Authors: Abdou, Houssein S., Bergeron, Francis, Tremblay, Jacques J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248749/
https://ncbi.nlm.nih.gov/pubmed/25225331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00734-14
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