Glucocorticoid and Mineralocorticoid Receptor Expression in the Human Hippocampus in Major Depressive Disorder

Approximately 50% of mood disorder patients exhibit hypercortisolism. Cortisol normally exerts its functions in the CNS via binding to mineralocorticoid receptors (MR) and glucocorticoid receptors (GR). Both MR and GR are highly expressed in human hippocampus and several studies have suggested that...

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Detalhes bibliográficos
Publicado no:J Psychiatr Res
Main Authors: Medina, Adriana, Seasholtz, Audrey F., Sharma, Vikram, Burke, Sharon, Bunney, William, Myers, Richard M., Schatzberg, Alan, Akil, Huda, Watson, Stanley J
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248661/
https://ncbi.nlm.nih.gov/pubmed/23219281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpsychires.2012.11.002
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