Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson’s disease

INTRODUCTION: Lewy body and Alzheimer-type pathologies often co-exist. Several studies suggest a synergistic relationship between amyloid-β (Aβ) and α-synuclein (α-syn) accumulation. We have explored the relationship between Aβ accumulation and the phosphorylation of α-syn at serine-129 (pSer129 α-s...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Swirski, Marta, Miners, J Scott, de Silva, Rohan, Lashley, Tammaryn, Ling, Helen, Holton, Janice, Revesz, Tamas, Love, Seth
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248436/
https://ncbi.nlm.nih.gov/pubmed/25452767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-014-0077-y
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