Different sites of acivicin binding and inactivation of gamma-glutamyl transpeptidases.
Acivicin is a potent inhibitor of gamma-glutamyl transpeptidase (EC 2.3.2.2), an enzyme of importance in glutathione metabolism. Acivicin inhibition and binding are prevented by gamma-glutamyl substrates and analogs (e.g., serine plus borate), consistent with the previous postulate that acivicin and...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7892271/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.6.2360 |
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