Differential spatial and structural organization of the X chromosome underlies dosage compensation in C. elegans

The adjustment of X-linked gene expression to the X chromosome copy number (dosage compensation [DC]) has been widely studied as a model of chromosome-wide gene regulation. In Caenorhabditis elegans, DC is achieved by twofold down-regulation of gene expression from both Xs in hermaphrodites. We show...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Sharma, Rahul, Jost, Daniel, Kind, Jop, Gómez-Saldivar, Georgina, van Steensel, Bas, Askjaer, Peter, Vaillant, Cédric, Meister, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248290/
https://ncbi.nlm.nih.gov/pubmed/25452271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.248864.114
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados