Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis

Down-regulation of miR-26 family members has been implicated in the pathogenesis of multiple malignancies. In some settings, including glioma, however, miR-26-mediated repression of PTEN promotes tumorigenesis. To investigate the contexts in which the tumor suppressor versus oncogenic activity of mi...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Zeitels, Lauren R., Acharya, Asha, Shi, Guanglu, Chivukula, Divya, Chivukula, Raghu R., Anandam, Joselin L., Abdelnaby, Abier A., Balch, Glen C., Mansour, John C., Yopp, Adam C., Richardson, James A., Mendell, Joshua T.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248289/
https://ncbi.nlm.nih.gov/pubmed/25395662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.250951.114
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