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An ENU-induced mutation in the mouse Rnf212 gene is associated with male meiotic failure and infertility

The ENU-induced repro57 mutation was identified in an unbiased screen for the discovery of novel genes for fertility. Male repro57 homozygous mice are infertile, and exhibit significantly reduced testis weight compared to wild type. Histological examination of mutant testes revealed that spermatocyt...

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Détails bibliographiques
Publié dans:Reproduction
Auteurs principaux: Fujiwara, Yasuhiro, Matsumoto, Hirokazu, Akiyama, Kouyou, Srivastava, Anuj, Chikushi, Mizuho, Handel, Mary Ann, Kunieda, Tetsuo
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248014/
https://ncbi.nlm.nih.gov/pubmed/25342176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-14-0122
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