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Hypothesis Testing for an Extended Cox Model with Time-Varying Coefficients

The log-rank test has been widely used to test treatment effects under the Cox model for censored time-to-event outcomes, though it may lose power substantially when the model’s proportional hazards assumption does not hold. In this paper, we consider an extended Cox model that uses B-splines or smo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biometrics
Hauptverfasser: Saegusa, Takumi, Di, Chongzhi, Chen, Ying Qing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247822/
https://ncbi.nlm.nih.gov/pubmed/24888739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/biom.12185
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