Lower glutamic acid decarboxylase 65kD mRNA and protein levels in the prefrontal cortex in schizoaffective disorder but not schizophrenia

BACKGROUND: Altered GABA signaling in the prefrontal cortex (PFC) has been associated with cognitive dysfunction in schizophrenia and schizoaffective disorder. PFC levels of the GABA-synthesizing enzyme glutamic acid decarboxylase 67kD (GAD67) has been consistently reported to be lower in these diso...

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Xehetasun bibliografikoak
Argitaratua izan da:Biol Psychiatry
Egile Nagusiak: Glausier, JR, Kimoto, S, Fish, KN, Lewis, DA
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247819/
https://ncbi.nlm.nih.gov/pubmed/24993056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2014.05.010
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