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Verification of 50- to 100-mer DNA and RNA sequences with high-resolution mass spectrometry.

Electrospray ionization with Fourier-transform mass spectrometry achieves accurate (< 50-ppm) determination of molecular weights of nucleotides, verifying structures of biological RNA and synthetic single-stranded DNA. High (1o(5)) resolving power makes possible detection of subpicomole impuritie...

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Bibliografische gegevens
Hoofdauteurs: Little, D P, Thannhauser, T W, McLafferty, F W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC42474/
https://ncbi.nlm.nih.gov/pubmed/7534419
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