Melting analysis on microbeads in rapid temperature-gradient inside microchannels for single nucleotide polymorphisms detectiona)

A continuous-flow microchip with a temperature gradient in microchannels was utilized to demonstrate spatial melting analysis on microbeads for clinical Single Nucleotide Polymorphisms (SNPs) genotyping on animal genomic DNA. The chip had embedded heaters and thermometers, which created a rapid and...

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Bibliographic Details
Published in:Biomicrofluidics
Main Authors: Li, Kan-Chien, Ding, Shih-Torng, Lin, En-Chung, Wang, Lon (Alex), Lu, Yen-Wen
Format: Artigo
Language:Inglês
Published: AIP Publishing LLC 2014
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247367/
https://ncbi.nlm.nih.gov/pubmed/25553186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4902907
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