CD8+ T cells suppress human immunodeficiency virus replication by inhibiting viral transcription.

CD8+ cells from human immunodeficiency virus (HIV)-infected individuals suppress HIV replication in cultured CD4+ cells by a noncytolytic mechanism that involves a secreted CD8(+)-cell antiviral factor (CAF). The results of this study suggest that CD8+ cells, as well as CAF, arrest HIV replication a...

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Main Authors: Mackewicz, C E, Blackbourn, D J, Levy, J A
格式: Artigo
語言:Inglês
出版: 1995
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC42473/
https://ncbi.nlm.nih.gov/pubmed/7534418
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