The impact of human and mouse differences in NOS2 gene expression on the brain’s redox and immune environment

BACKGROUND: Mouse models are used in the study of human disease. Despite well-known homologies, the difference in immune response between mice and humans impacts the application of data derived from mice to human disease outcomes. Nitric oxide synthase-2 (NOS2) is a key gene that displays species-sp...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Hoos, Michael D, Vitek, Michael P, Ridnour, Lisa A, Wilson, Joan, Jansen, Marilyn, Everhart, Angela, Wink, David A, Colton, Carol A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247207/
https://ncbi.nlm.nih.gov/pubmed/25403885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-9-50
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