Enterotoxicity of a nonribosomal peptide causes antibiotic-associated colitis

Antibiotic therapy disrupts the human intestinal microbiota. In some patients rapid overgrowth of the enteric bacterium Klebsiella oxytoca results in antibiotic-associated hemorrhagic colitis (AAHC). We isolated and identified a toxin produced by K. oxytoca as the pyrrolobenzodiazepine tilivalline a...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Schneditz, Georg, Rentner, Jana, Roier, Sandro, Pletz, Jakob, Herzog, Kathrin A. T., Bücker, Roland, Troeger, Hanno, Schild, Stefan, Weber, Hansjörg, Breinbauer, Rolf, Gorkiewicz, Gregor, Högenauer, Christoph, Zechner, Ellen L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246982/
https://ncbi.nlm.nih.gov/pubmed/25157164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403274111
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires