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Three-dimensional cell body shape dictates the onset of traction force generation and growth of focal adhesions

Cell shape affects proliferation and differentiation, which are processes known to depend on integrin-based focal adhesion (FA) signaling. Because shape results from force balance and FAs are mechanosensitive complexes transmitting tension from the cell structure to its mechanical environment, we in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fouchard, Jonathan, Bimbard, Célian, Bufi, Nathalie, Durand-Smet, Pauline, Proag, Amsha, Richert, Alain, Cardoso, Olivier, Asnacios, Atef
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246942/
https://ncbi.nlm.nih.gov/pubmed/25157134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411785111
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