Progression to AIDS in SIV-Infected Rhesus Macaques is Associated with Distinct KIR and MHC class I Polymorphisms and NK Cell Dysfunction

Killer cell immunoglobulin-like receptors (KIR) regulate the activity of natural killer (NK) cells and have been shown to be associated with susceptibility to a number of human infectious diseases. Here, we analyzed NK cell function and genetic associations in a cohort of 52 rhesus macaques experime...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Albrecht, Christina, Malzahn, Dörthe, Brameier, Markus, Hermes, Meike, Ansari, Aftab A., Walter, Lutz
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246914/
https://ncbi.nlm.nih.gov/pubmed/25506344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00600
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