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Raf kinase inhibitor protein inhibits cholangiocarcinoma cell metastasis by downregulating matrix metalloproteinase 9 and upregulating tissue inhibitor of metalloproteinase 4 expression

Cholangiocarcinoma cells originate in the biliary epithelium. The cells easily metastasize and cause relapse. The effect of Raf kinase inhibitor protein (RKIP) on the biological behavior of cholangiocarcinoma cells is not yet clear. In the present study, RKIP and cytokeratin 19 expression was detect...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: MA, JUNJI, SHI, JUNLI, ZHAO, DONGQIANG, CHENG, LIJUAN, WANG, WENBIN, LI, FANGFANG, JIANG, XIAOYU, JIANG, HUIQING
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246646/
https://ncbi.nlm.nih.gov/pubmed/25435928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2637
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