ABCB5 is a limbal stem cell gene required for corneal development and repair

Corneal epithelial homeostasis and regeneration are sustained by limbal stem cells (LSCs)(1–3), and LSC deficiency is a major cause of blindness worldwide(4). Transplantation is often the only therapeutic option available to patients with LSC deficiency. However, while transplant success depends for...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Ksander, Bruce R., Kolovou, Paraskevi E., Wilson, Brian J., Saab, Karim R., Guo, Qin, Ma, Jie, McGuire, Sean P., Gregory, Meredith S., Vincent, William J. B., Perez, Victor L., Cruz-Guilloty, Fernando, Kao, Winston W. Y., Call, Mindy K., Tucker, Budd A., Zhan, Qian, Murphy, George F., Lathrop, Kira L., Alt, Clemens, Mortensen, Luke J., Lin, Charles P., Zieske, James D., Frank, Markus H., Frank, Natasha Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246512/
https://ncbi.nlm.nih.gov/pubmed/25030174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13426
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