Excess cholesterol induces mouse egg activation and may cause female infertility

The HDL receptor scavenger receptor, class B type I (SR-BI) controls the structure and fate of plasma HDL. Female SR-BI KO mice are infertile, apparently because of their abnormal cholesterol-enriched HDL particles. We examined the growth and meiotic progression of SR-BI KO oocytes and found that th...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Yesilaltay, Ayce, Dokshin, Gregoriy A., Busso, Dolores, Wang, Li, Galiani, Dalia, Chavarria, Tony, Vasile, Eliza, Quilaqueo, Linda, Orellana, Juan Andrés, Walzer, Dalia, Shalgi, Ruth, Dekel, Nava, Albertini, David F., Rigotti, Attilio, Page, David C., Krieger, Monty
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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PNAS Plus
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246315/
https://ncbi.nlm.nih.gov/pubmed/25368174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418954111
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