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Cells infected with herpes simplex virus 1 export to uninfected cells exosomes containing STING, viral mRNAs, and microRNAs

STING (stimulator of IFN genes) activates the IFN-dependent innate immune response to infection on sensing the presence of DNA in cytosol. The quantity of STING accumulating in cultured cells varies; it is relatively high in some cell lines [e.g., HEp-2, human embryonic lung fibroblasts (HEL), and H...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Kalamvoki, Maria, Du, Te, Roizman, Bernard
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246290/
https://ncbi.nlm.nih.gov/pubmed/25368198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1419338111
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