siRNAs from an X-linked satellite repeat promote X-chromosome recognition in Drosophila melanogaster

Highly differentiated sex chromosomes create a lethal imbalance in gene expression in one sex. To accommodate hemizygosity of the X chromosome in male fruit flies, expression of X-linked genes increases twofold. This is achieved by the male- specific lethal (MSL) complex, which modifies chromatin to...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Menon, Debashish U., Coarfa, Cristian, Xiao, Weimin, Gunaratne, Preethi H., Meller, Victoria H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246271/
https://ncbi.nlm.nih.gov/pubmed/25368194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410534111
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