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Brominated Flame Retardants, Tetrabromobisphenol A and Hexabromocyclododecane, Activate Mitogen-Activated Protein Kinases (MAPKs) in Human Natural Killer Cells

NK cells provide a vital surveillance against virally infected cells, tumor cells, and antibody-coated cells through the release of cytolytic mediators and gamma interferon (IFN-γ). Hexabromocyclododecane (HBCD) is a brominated flame retardant used primarily in expanded (EPS) and extruded (XPS) poly...

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Detalhes bibliográficos
Publicado no:Cell Biol Toxicol
Main Authors: Cato, Anita, Celada, Lindsay, Kibakaya, Esther Caroline, Simmons, Nadia, Whalen, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246052/
https://ncbi.nlm.nih.gov/pubmed/25341744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10565-014-9289-y
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