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Enhanced innate anti-viral gene expression, interferon-α, and cytolytic responses are predictive of mucosal immune recovery during SIV infection

The mucosa that lines the respiratory and gastrointestinal (GI) tracts is an important portal of entry for pathogens and provides the first line of innate immune defense against infections. Although an abundance of memory CD4+ T-cells at mucosal sites render them highly susceptible to HIV infection,...

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Библиографические подробности
Опубликовано в: :J Immunol
Главные авторы: Verhoeven, David, George, Michael D., Hu, Will, Dang, Angeline T., Smit-McBride, Zeljka, Reay, Elizabeth, Macal, Monica, Fenton, Anne, Sankaran-Walters, Sumathi, Dandekar, Satya
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246033/
https://ncbi.nlm.nih.gov/pubmed/24610016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302415
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