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Transcription bypass of DNA lesions enhances cell survival but attenuates transcription coupled DNA repair

Transcription-coupled DNA repair (TCR) is a subpathway of nucleotide excision repair (NER) dedicated to rapid removal of DNA lesions in the transcribed strand of actively transcribed genes. The precise nature of the TCR signal and how the repair machinery gains access to lesions imbedded in stalled...

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Publicat a:Nucleic Acids Res
Autors principals: Li, Wentao, Selvam, Kathiresan, Ko, Tengyu, Li, Shisheng
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245964/
https://ncbi.nlm.nih.gov/pubmed/25389266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1150
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