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Integrated mechanism for the generation of the 5′ junctions of LINE inserts

To elucidate the molecular mechanism of the integration of long interspersed elements (LINEs), we characterized the 5′ ends of more than 200 LINE de novo retrotransposition events into chicken DT40 or human HeLa cells. Human L1 inserts produced 15-bp target-site duplications (TSDs) and zebrafish ZfL...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Yamaguchi, Katsumi, Kajikawa, Masaki, Okada, Norihiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245944/
https://ncbi.nlm.nih.gov/pubmed/25378331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1067
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