Inducible forebrain-specific ablation of the transcription factor Creb during adulthood induces anxiety but no spatial/contextual learning deficits

The cyclic AMP (cAMP)-response element binding protein (CREB) is an activity-dependent transcription factor playing a role in synaptic plasticity, learning and memory, and emotional behavior. However, the impact of Creb ablation on rodent behavior is vague as e.g., memory performance of different Cr...

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Опубликовано в: :Front Behav Neurosci
Главные авторы: Vogt, Miriam A., Inta, Dragos, Luoni, Alessia, Elkin, Hasan, Pfeiffer, Natascha, Riva, Marco A., Gass, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2014
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245921/
https://ncbi.nlm.nih.gov/pubmed/25505876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnbeh.2014.00407
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