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Alterations in cytotoxic and helper T cell function after infection of T cell clones with human T cell leukemia virus, type I.

HTLV-I is a transforming human retrovirus that is an etiologic agent of adult T cell leukemia/lymphoma. To investigate the effects of this virus on T cell functions, two OKT3+, OKT4+, OKT8- cytotoxic clones (8.7 and 8.8) specific for allogeneic cells bearing DPw2, a class II histocompatibility antig...

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Bibliographic Details
Main Authors: Yarchoan, R, Guo, H G, Reitz, M, Maluish, A, Mitsuya, H, Broder, S
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC424547/
https://ncbi.nlm.nih.gov/pubmed/3009545
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