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A critical role for the transcription factor Fli-1 in lupus development by regulating expression of Interleukin 6

OBJECTIVE: The Fli-1 transcription factor is implicated in the pathogenesis of systemic lupus erythematosus (SLE) in both human patients and animal models. Dysregulation of interleukin 6 (IL-6) is also associated with SLE. We investigated whether Fli-1 directly regulates the expression of IL-6. METH...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Sato, Shuzo, Richard, Mara Lennard, Brandon, Danielle, Jones Buie, Joy N., Oates, Jim, Gilkeson, Gary, Zhang, Xian K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245454/
https://ncbi.nlm.nih.gov/pubmed/25155007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38818
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