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A Method to Evaluate the Effect of Contact with Excipients on the Surface Crystallization of Amorphous Drugs

Amorphous drugs are used to improve the solubility, dissolution, and bioavailability of drugs. However, these metastable forms of drugs can transform into more stable, less soluble, crystalline counterparts. This study reports a method for evaluating the effect of commonly used excipients on the sur...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Zhang, Si-Wei, Yu, Lian, Huang, Jun, Hussain, Munir A., Derdour, Lotfi, Qian, Feng, de Villiers, Melgardt M.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245425/
https://ncbi.nlm.nih.gov/pubmed/25037732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0178-8
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