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Tissue plasminogen activator promotes platelet disaggregation in plasma.

We studied the disaggregation of human platelets by tissue-type plasminogen activator (t-PA). When added to a suspension of human platelets induced to aggregate in plasma with adenosine 5'-diphosphate, t-PA promoted disaggregation of platelets over several minutes. Addition of fresh plasma or p...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Loscalzo, J, Vaughan, D E
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1987
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2438305/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113015
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