Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome

[Image: see text] Despite decades of research on the bacterial ribosome, the ribosomal exit tunnel is still poorly understood. Although it has been suggested that the exit tunnel is simply a convenient route of egress for the nascent chain, specific protein sequences serve to slow the rate of transl...

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Udgivet i:ACS Chem Biol
Main Authors: Washington, Arren Z., Benicewicz, Derek B., Canzoneri, Joshua C., Fagan, Crystal E., Mwakwari, Sandra C., Maehigashi, Tatsuya, Dunham, Christine M., Oyelere, Adegboyega K.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245169/
https://ncbi.nlm.nih.gov/pubmed/25198768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5003224
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