Eyelid Closure in Embryogenesis Is Required for Ocular Adnexa Development

PURPOSE. Mammalian eye development requires temporary fusion of the upper and lower eyelids in embryogenesis. Failure of lid closure in mice leads to an eye open at birth (EOB) phenotype. Many genetic mutant strains develop this phenotype and studies of the mutants lead to a better understanding of...

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Publié dans:Invest Ophthalmol Vis Sci
Auteurs principaux: Meng, Qinghang, Mongan, Maureen, Carreira, Vinicius, Kurita, Hisaka, Liu, Chia-yang, Kao, Winston W.-Y., Xia, Ying
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2014
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245069/
https://ncbi.nlm.nih.gov/pubmed/25377219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15155
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