Eyelid Closure in Embryogenesis Is Required for Ocular Adnexa Development

PURPOSE. Mammalian eye development requires temporary fusion of the upper and lower eyelids in embryogenesis. Failure of lid closure in mice leads to an eye open at birth (EOB) phenotype. Many genetic mutant strains develop this phenotype and studies of the mutants lead to a better understanding of...

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Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Meng, Qinghang, Mongan, Maureen, Carreira, Vinicius, Kurita, Hisaka, Liu, Chia-yang, Kao, Winston W.-Y., Xia, Ying
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2014
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245069/
https://ncbi.nlm.nih.gov/pubmed/25377219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-15155
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