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Regulation of lymphokine production and human T lymphocyte activation by 1,25-dihydroxyvitamin D3. Specific inhibition at the level of messenger RNA.

The steroid hormone, 1 alpha,25-dihydroxyvitamin D3 (calcitriol), has been shown to inhibit T cell proliferation, primarily through inhibition of interleukin 2 (IL-2) production. In these experiments, we show that calcitriol also markedly inhibited production of the lymphokine, gamma interferon (IFN...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Rigby, W F, Denome, S, Fanger, M W
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1987
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424495/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2884234/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113004
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