Sodium-potassium pump, ion fluxes, and cellular dehydration in sickle cell anemia.

We studied the role of the sodium-potassium pump in erythrocytes of 12 patients with sickle cell anemia (SS). Ouabain-binding sites per cell and pump-mediated Rb/K uptake were significantly higher in SS patients than in white or black controls. Ouabain-resistant Rb/K influx was also greater than in...

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izdano v:	J Clin Invest
Principais autores:	Izumo, H, Lear, S, Williams, M, Rosa, R, Epstein, F H
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Clinical Investigation 1987
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC424484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3034977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI112998
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