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DISTILLING PATHOPHYSIOLOGY FROM COMPLEX DISEASE GENETICS

Technologies for genome-wide sequence interrogation have dramatically improved our ability to identify loci associated with complex human disease. However, a chasm remains between correlations and causality that stems, in part, from a limiting theoretical framework derived from Mendelian genetics, a...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Chakravarti, Aravinda, Clark, Andrew G., Mootha, Vamsi K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244836/
https://ncbi.nlm.nih.gov/pubmed/24074858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.09.001
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