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Targeting PPM1D by lentivirus-mediated RNA interference inhibits the tumorigenicity of bladder cancer cells

Protein phosphatase magnesium/manganese-dependent 1D (PPM1D) is a p53-induced phosphatase that functions as a negative regulator of stress response pathways and has oncogenic properties. However, the functional role of PPM1D in bladder cancer (BC) remains largely unknown. In the present study, lenti...

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Bibliographische Detailangaben
Veröffentlicht in:Braz J Med Biol Res
Hauptverfasser: Wang, W., Zhu, H., Zhang, H., Zhang, L., Ding, Q., Jiang, H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associação Brasileira de Divulgação Científica 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244669/
https://ncbi.nlm.nih.gov/pubmed/25387670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20143645
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