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Markers of apoptosis induction and proliferation in the orbitofrontal cortex in alcohol dependence

BACKGROUND: Alcohol-dependent (ALC) subjects exhibit glial and neuronal pathology in the prefrontal cortex (PFC). However, in many patients, neurophysiological disturbances are not associated with catastrophic cell depletion despite prolonged alcohol abuse. It is still unclear how some relevant mark...

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Publicado en:Alcohol Clin Exp Res
Autores principales: Whittom, Angela, Villarreal, Ashley, Soni, Madhav, Owusu-Duku, Beverly, Meshram, Ashish, Rajkowska, Grazyna, Stockmeier, Craig A., Miguel-Hidalgo, Jose J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244601/
https://ncbi.nlm.nih.gov/pubmed/25421516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12559
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