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Mechanisms of polymyxin resistance: acquired and intrinsic resistance in bacteria

Polymyxins are polycationic antimicrobial peptides that are currently the last-resort antibiotics for the treatment of multidrug-resistant, Gram-negative bacterial infections. The reintroduction of polymyxins for antimicrobial therapy has been followed by an increase in reports of resistance among G...

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Veröffentlicht in:Front Microbiol
Hauptverfasser: Olaitan, Abiola O., Morand, Serge, Rolain, Jean-Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244539/
https://ncbi.nlm.nih.gov/pubmed/25505462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2014.00643
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