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Neuronal Regeneration in C. elegans Requires Subcellular Calcium Release by Ryanodine Receptor Channels and Can Be Enhanced by Optogenetic Stimulation

Regulated calcium signals play conserved instructive roles in neuronal repair, but how localized calcium stores are differentially mobilized, or might be directly manipulated, to stimulate regeneration within native contexts is poorly understood. We find here that localized calcium release from the...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Sun, Lin, Shay, James, McLoed, Melissa, Roodhouse, Kevin, Chung, Samuel H., Clark, Christopher M., Pirri, Jennifer K., Alkema, Mark J., Gabel, Christopher V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244466/
https://ncbi.nlm.nih.gov/pubmed/25429136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4238-13.2014
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